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youtu.be/LHdYfFGrXIgThis is part 1 of my interview with Dr Neil Shaw from the Tower Clinic 1# Introductions and overview. Why do people go low carb? What medical conditions can ...
Noopept is a racetam-like compound, similar to Piracetam which are a group of synthetic supplements intended to provide a cognitive boost, AKA smart drugs or nootropics. 🤩
💊The effects of Noopept seem to vary from user to user. Some experience a very small change in their memory and cognitive abilities, while others experience a huge increases in memory and capacity to recall small details.
🧪I had very positive effects from Noopept and I used the nasal spray form, from optimresearch.com which was better then the powder form. I preferred Noopept to Piracetam and it is much stronger, requiring a much smaller doses. Noopept was a good pre-workout for me, yet didn’t give me insomnia.
📉Noopept stimulates the AMPA and NMDA receptors and their pathways, which play roles in memory and thought processes. The neuro-protective qualities of Noopept are believed to be via stimulation of a protein known as Nerve Growth Hormones (NGH) which plays an active role in reducing and even preventing neuronal degeneration in the hippocampus and Brain-Derived Neurotrophic Factor (BDNF) which deals with thethe growth and differentiation of new neurons and synapses. Increasing BDNF can help with some types of depression
📈Studies show that Noopept was beneficial in restoring some cognition in regard to Alzheimer’s disease and Parkinson’s. In addition it was shown to prevent free radicals and pro-inflammatory cytokines accumulation, ionic imbalance, neurotrophin deficit and excitotoxicity. (Ostrovskaya, & et. al, 2014). 📊The data is mixed on whether Noopept only helps impaired brains.
Noopept is non toxic with minimal know side effects in both short and long term studies, but it still requires more research to fully understand its biological mechanisms. #neuroscience #smartdrugs
Gluconeogenesis is something that people on a low carb / keto diet fear, but why?
📈Gluconeogenesis is a process that occurs in the liver when we need energy eg during heavy exercise, fasting, cutting carbs or calories and when insulin is low . Gluconeogenesis involves making glucose from certain non-carbohydrate sources such as proteins, pyruvate, lactate & glycerol.
📈So people fear that this “internally produced glucose “ will spike insulin and bring them out of ketosis. There is an element of truth in this, but it won’t by any means ruin a low carb diet!
😃In humans the main substrates or building block to make glucose are lactate, glycerol alanine (amino acid) and glutamine (amino acid) & they account for over 90% of the overall gluconeogenesis.
When we fast, go keto/ low carb, exercise glycogen (animal starch) is depleted and glucagon levels rise. Glucagon is a hormone which opposes insulin by mobilising energy stores, where as insulin is a storage hormone.
Glucagon activates lioplysis (fat breakdown), insulin will be low if glucagon is high so the liver can’t store fat.
🕴🏻When you deplete glycogen, gluconeogenesis will increase and fat oxidation will increase which is what we want. 🍽🏃♀️Fasting and excercise won’t induce real medical hypoglycaemia because of Gluconeogenesis and this is a great thing ! Otherwise fasted cardio, keto or just a fast would be a painful and dangerous
If you are in ketosis - gluconeogenesis will happen in parallel, this is biology.
We need gluconeogenesis to do low carb, exercise and feed cells which can’t use ketones like red blood cells.
🍚You will produce your own glucose after a work out if you are in ketosis another great thing about gluconeogenesis.
It is true some protein can activate gluconeogenesis others can be insulinogenic 🥥Fat increases glucagon
🍞🍪Starch / sugar increases insulin
🍤🥩Protein increases glucagon and insulin (muscle doesn’t have many glucagon receptors) glucagon is catabolic (breaks things down) but not muscle
#ketosis #lowcarb #biochemistry
I am making audio versions of my blogs and this one is on insulin, ketones, salt and 'fat traps'
A fat trap is sort of a biochemical situation people get into and then struggle with their weight
youtu.be/_g2zDSe6r7YHello and welcome! This is my first audio version of one of my blog posts called Insulin, Salt and Fat Traps Its is a useful listen for anyone interested in ...
Chronic biochemical inflammation has its hand in numerous conditions and illness in people of all ages and backgrounds.
Inflammatory markers are measured using blood tests.
C-reactive protein is what is commonly used but it is one reading on its own, so can be misleading.
Here are a list of more, you can order them to get a full inflammation profile
Homo cysteine low or high (above 9 below 7)
Uric acid - high
High white blood cells high (higher than 8)
Insulin - high
Neutrophils higher than 60%
Eosinphils higher than 3%
CD8/CD4 ratio
pH should be 6.6 -7.0 (wee on a stick in day and take the average).
#inflammation #biohacking
